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Combined application of optic nerve sheath diameter and ventricular time integral in cardiac function assessment and volume management of preeclampsia pregnant women

Combined application of optic nerve sheath diameter and ventricular time integral in cardiac function assessment and volume management of preeclampsia pregnant women

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118015
Enrollment
Unknown
Registered
2026-01-30
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia

Interventions

Observation group:None

Sponsors

Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.Preeclampsia patients with an ASA (American Society of Anesthesiologists) physical status classification of III and aged between 18 and 45 years old. 2.Patients meeting the diagnostic criteria for preeclampsia, which include the onset of systolic blood pressure >=140 mmHg and/or diastolic blood pressure >=90 mmHg after 20 weeks of gestation, accompanied by proteinuria >=0.3 g/24 h or random proteinuria = (+), or, in the absence of proteinuria, the presence of any of the following conditions: thrombocytopenia (platelet count 1.1 mg/dL or an increase of more than 0.5 mg/dL from pre-pregnancy levels), pulmonary edema, or newly developed cerebral or visual dysfunction.

Exclusion criteria

Exclusion criteria: 1.Patients with concurrent cardiovascular diseases, intracranial lesions, ocular diseases, or other conditions that may affect ONSD or cardiac function; 2.Patients with allergies to anesthetic drugs or existing contraindications to anesthesia; 3.Maternal participants who have participated in other clinical trials within the past three months prior to enrollment or are currently participating in other clinical trials; 4.Maternal participants for whom, in the judgment of the trial's responsible physician, participation in the trial may increase the risk to the subject or may result in insufficient trial data being obtained.

Design outcomes

Primary

MeasureTime frame
Optic Nerve Sheath Diameter;Velocity Time Integral;

Secondary

MeasureTime frame
Basic vital signs;

Countries

China

Contacts

Public ContactHuiying Zhang

Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital

279763402@qq.com+86 138 5169 0367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026