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Study on the Pathogenic Mechanism of PGAM1 in Osteoarthritis

Study on the Pathogenic Mechanism of PGAM1-Mediated Glycolytic Metabolism in Synovial Macrophages during Osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118012
Enrollment
Unknown
Registered
2026-01-30
Start date
2026-01-30
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, OA

Interventions

Healthy Control Group:None
OA group:None

Sponsors

TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Meet the diagnostic criteria of the American College of Rheumatology (ACR) with a Kellgren-Lawrence radiological grading of >= 3;

Exclusion criteria

Exclusion criteria: 1.History of systemic immune or infectious diseases;

Design outcomes

Primary

MeasureTime frame
The Effect of Targeted Intervention on PGAM1 on the Progression of Osteoarthritis;—

Countries

China

Contacts

Public ContactHainan Hong

TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE

honghn@enzemed.com+86 576 8512 0120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026