Tinnitus
Conditions
Interventions
experimental group:The experimental group underwent fMRI functional connectivity analysis to precisely identify the functional node in the left auditory cortex that exhibited the strongest connectivit
control group:In the control group, the stimulation target was determined according to the anatomical landmarks of the international 10–20 EEG system, corresponding to the left CP5 electrode site (ant
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients presenting primarily with tinnitus: individuals experiencing subjective auditory perceptions in the ear or deep within the head in the absence of internal or external sound stimuli. 2. Chronic tinnitus patients with a duration of =6 months, Tinnitus Handicap Inventory (THI) score =38, and unresponsive to conventional pharmacological treatment. 3. Patients able to undergo a continuous 5-day cTBS treatment course and who are outpatients at Sun Yat-sen Memorial Hospital, Sun Yat-sen University. 4. Tinnitus frequency ranging from 125 to 8000 Hz. 5. Age between 18 and 70 years.
Exclusion criteria
Exclusion criteria: 1. Patients with conductive hearing loss, a history of middle ear surgery, pulsatile tinnitus caused by vascular malformations, or tinnitus associated with Ménière’s disease. 2. History of head trauma, central nervous system disorders, psychiatric disorders, or substance abuse. 3. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective rate of chronic tinnitus relief; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in tinnitus loudness;Change in anxiety symptoms;Change in depressive symptoms;Change in sleep quality;Effective rate of tinnitus relief during intervention and follow-up; | — |
Countries
China
Contacts
Public ContactYuexin Cai
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Outcome results
None listed