Perioperative anxiety and depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing gynecological laparoscopic surgery under general anesthesia; 2. Age 18-65; 3. ASA I-II; 4. BMI 18-28 kg/m^2; 5. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. History of mental illnesses such as anxiety and depression; 2. Severe impairment of heart, liver, and kidney functions; 3. People with difficulties in understanding speech; 4. Allergic to remimazolam, dexmedetomidine, or opioids, with alcohol addiction, or long-term use of non-steroidal anti-inflammatory drugs; 5. History of chronic pain;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HADS scale scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 scale scores;Intraoperative Heart Rate and Blood Pressure;Intraoperative usage of propofol, remifentanil, vasopressors, and analgesics;Postoperative adverse reaction incidence;Pain scores at postoperative 24 hours and 72 hours; | — |
Countries
China
Contacts
The First Affiliated Hospital, Jinan University