Skin aging
Conditions
Interventions
control group:Only basic hydrating injection
AT- EV group:A composite preparation of fat tissue-derived exosomes and basic mesotherapy solution for superficial facial skin injection
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
25 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 25 and 55 years (inclusive), regardless of gender. 2.Mild to moderate facial aging (such as Glogau grade II-III), with no severe skin lesions (such as active dermatitis, infections, etc.). 3.No aesthetic medical treatments (such as laser, injectable fillers, etc.) in the past 3 months, and no use of medications affecting skin function in the past 4 weeks. 4.Understand and agree to the study requirements, voluntarily sign the informed consent form, and be able to complete all follow-up and assessments. 5.Non-pregnant and non-lactating women, with no plans for pregnancy during the study period. 6.Non-smokers or light smokers (=5 cigarettes per day).
Exclusion criteria
Exclusion criteria: 1.The participant has uncontrolled systemic diseases (such as cardiovascular disease, diabetes, malignancies). 2.The participant has immune system diseases or an immunosuppressive state (such as lupus, post-organ transplantation reactions). 3.The participant has severe skin conditions on the face (such as active dermatitis, infections, keloids). 4.The participant has severe mental health disorders, such as depression, anxiety, etc. 5.The participant has a history of prolonged, high-intensity sun exposure in the past 3 months (such as outdoor workers, frequent sunbathers, etc.). 6.The participant has previously participated in another interventional study, and the study ended less than 3 months ago.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in skin elasticity and pigmentation.; | — |
Countries
China
Contacts
Public ContactKai Liu
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed