Metabolic Associated Fatty Liver Disease Complicated with Helicobacter pylori Infection
Conditions
Interventions
HPET Group:Eradicate Helicobacter pylori
SMT Group:Dietary and exercise guidance
Sponsors
Dalian University Affiliated Xinhua Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Enroll patients from the outpatient and inpatient departments of Gastroenterology in our hospital, aged 18 to 65 years old, with a confirmed diagnosis of Helicobacter pylori infection and metabolism-associated fatty liver disease.
Exclusion criteria
Exclusion criteria: 1.History of previous pharmacologic eradication therapy for Helicobacter pylori infection; 2.hypersensitivity to any agent used in H. pylori eradication therapy; 3.presence of bacterial, viral or fungal infections requiring pharmacologic treatment; 4.history of liver cirrhosis, hepatic surgery or liver transplantation; 5.history of gastrointestinal tract neoplasms; 6.and patients with severe cardiac insufficiency or renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Indicators related to metabolic-associated fatty liver disease before and after eradication of Helicobacter pylori (including metabolic indicators, inflammatory indicators, CAP) improvement.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Microbiota and generations of fecal contents of patients before and after eradication of Helicobacter pylori Changes in omics characteristics; | — |
Countries
China
Contacts
Public ContactHe Yuan
Dalian University Affiliated Xinhua Hospital
Outcome results
None listed