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Comparison of unilateral versus bilateral medial rectus botulinum toxin A injection for acute acquired comitant esotropia: A prospective randomized controlled trial

Comparison of unilateral versus bilateral medial rectus botulinum toxin A injection for acute acquired comitant esotropia: A prospective randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117977
Enrollment
Unknown
Registered
2026-01-30
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute acquired comitant esotropia

Interventions

Bilateral injection group:Botulinum toxin A injection into both medial rectus muscles
Unilateral injection group:Injection of botulinum toxin A into the unilateral medial rectus muscle

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=8 years old; 2.Diagnosed with acute acquired comitant esotropia; 3.Strabismus deviation <=50 PD; 4.Presenting with diplopia; 5.No prior treatment with BTXA;

Exclusion criteria

Exclusion criteria: 1.History of prior strabismus surgery or ocular trauma; 2.Hypersensitivity to BTXA; 3.Concurrent neurological disorders; 4.Pregnancy or lactation; 5.Inability to complete follow-up;

Design outcomes

Primary

MeasureTime frame
Degree of strabismus;—

Countries

China

Contacts

Public ContactNing Hua

Tianjin Medical University Eye Hospital

tian2815@sina.com+86 186 4900 1105

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026