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Clinical Efficacy and Neural Mechanisms of Dual-target Task-integrated rTMS for the Treatment of Post-stroke Language and Motor Comorbid Disorders

Clinical Efficacy and Neural Mechanisms of Dual-target Task-integrated rTMS for the Treatment of Post-stroke Language and Motor Comorbid Disorders

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117961
Enrollment
Unknown
Registered
2026-01-30
Start date
2026-01-31
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The study aims to evaluate the therapeutic effects of the dual-target, task-integrated rTMS intervention on post-stroke aphasia and motor dysfunction.

Interventions

sham TMS group:placebo stimulation
Treatment Group:Dual-target rTMS
Control Group:Single Target rTMS

Sponsors

Affiliated Hospital of Hangzhou Normal University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with stroke according to the Chinese Guidelines for the Diagnosis and Treatment of Cerebral Haemorrhage (2019) or the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2018); 2. First-time onset with stable condition; 3. Native Chinese speaker with normal language and motor function prior to onset; 4. Diagnosed with aphasia, right-handed.

Exclusion criteria

Exclusion criteria: 1. Individuals with unstable vital signs and severe underlying medical conditions; 2. History of stroke, neurological or psychiatric disorders, alcoholism, or substance abuse; 3. Presence of metallic implants, electronic devices, or cranial defects; 4. Severe articulation disorders; 5. Concurrent severe dysfunction of vital organs such as heart, lungs, or liver; 6. Refusal to participate in this study.

Design outcomes

Primary

MeasureTime frame
Cognitive Behaviour;life skills;brain function;

Countries

China

Contacts

Public ContactZhang Ye

Affiliated Hospital of Hangzhou Normal University

zhye@hznu.edu.cn+86 571 2886 7717

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026