Postoperative Sleep Disorder
Conditions
Interventions
Group S+L:After entering the operating room, patients underwent stellate ganglion block (SGB) with 4 mL of 0.375% ropivacaine. A loading dose of 0.5 mg/kg esketamine was intravenously administered 1 m
Group S+C:After entering the operating room, patients received SGB with 4 mL of 0.375% ropivacaine. An equal volume of placebo (normal saline) was intravenously injected 1 minute before skin incision.
Group C+L:After entering the operating room, patients underwent SGB with 4 mL of normal saline. A loading dose of 0.5 mg/kg esketamine was intravenously given 1 minute before skin incision.
Group C+C:After entering the operating room, patients received SGB with 4 mL of normal saline. An equal volume of placebo (normal saline) was intravenously administered 1 minute before skin incision.
Sponsors
North China University of Science and Technology Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 to 65 years old; 2. American Society of Anesthesiologists (ASA) physical status classification ? and ?; 3. Body Mass Index (BMI): 18 to 30 kg/m²; 4. Patients undergoing general anesthesia with an expected operation duration of more than 1 hour.
Exclusion criteria
Exclusion criteria: 1. Preoperative neuropsychiatric diseases, cognitive or communication disorders, severe hepatic and renal dysfunction; 2. Known allergy or contraindications to esketamine; 3. Preoperative use of opioid analgesics; 4. Intraoperative conversion to laparotomy or postoperative admission to the Intensive Care Unit (ICU).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| State Entropy (SE);Response Entropy (RE);Burst Suppression Ratio (BSR); | — |
Countries
China
Contacts
Public ContactTiejun Liu
North China University of Science and Technology Affiliated Hospital
Outcome results
None listed