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Causal Inference between M2 Macrophage Traits and Mitochondrial Function in Keloid Fibroblasts

Causal Inference between M2 Macrophage Traits and Mitochondrial Function in Keloid Fibroblasts: A Mendelian Randomization and Single-Cell RNA-seq Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117934
Enrollment
Unknown
Registered
2026-01-30
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keloid

Interventions

Keloid Group:NA

Sponsors

The First Affiliated Hospital of Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with clinically confirmed keloids, where the skin lesions are located on non-plantar areas of the body, with lesion dimensions of at least 3 cm × 2 cm in both the longitudinal and transverse axes, and who have not received any prior local or systemic treatment.

Exclusion criteria

Exclusion criteria: History of corticosteroid injections, chronic skin diseases, metabolic disorders, autoimmune diseases, and malignant tumors.

Design outcomes

Primary

MeasureTime frame
mitochondrial functional status;M2 macrophage levels or distribution;—

Countries

China

Contacts

Public ContactZhang Qiguo

The First Affiliated Hospital of Xiamen University

zqgdreamer@163.com+86 572 213 7441

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026