Hylicobacter pylori infection
Conditions
Interventions
Group A:Vonoprazan 20mg twice a day taken 30 minutes before breakfast and dinner Amoxicillin 1.0g taken three times a day (half an hour after the meal) ,14day
Group B:Vonoprazan 20mg twice a day taken 30 minutes after breakfast and dinner Amoxicillin 1.0g taken three times a day (half an hour after the meal) ,14day
Sponsors
Wuxi people’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 18 - 70 years old; 2.Patients who have been diagnosed as positive for Helicobacter pylori; 3.Patients who have not previously received Helicobacter pylori eradication treatment; 4.Patients who voluntarily participate in this trial and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Allergic to the studied drugs; 2.Patients with active peptic ulcers; 3.Patients who have received treatment for Helicobacter pylori eradication within the past six months; 4.Using adrenal cortical hormones, non-steroidal anti-inflammatory drugs or anticoagulants; 5.History of esophageal or gastric surgery; 6.Pregnant women and lactating women; 7.Having severe accompanying diseases, such as liver diseases, cardiovascular diseases, lung diseases, and kidney diseases; 8.Gastric mucosa-associated lymphoid tissue lymphoma (MALT), malignant tumor diseases;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eradication rates; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance;Adverse event; | — |
Countries
China
Contacts
Public ContactQinglin Zhang
Wuxi People's Hospital Affiliated to Nanjing Medical University
Outcome results
None listed