Pain after Esophageal Endoscopic Submucosal Dissection
Conditions
Interventions
Dexamethasone Group:Patients in the Dexamethasone Group received an intravenous injection of dexamethasone (0.15 mg/kg) immediately after ESD.
Control Group:Those in the Control Group received an equivalent volume of normal saline.
Sponsors
Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Voluntary participation, confirmed by written informed consent. 2. Aged between 18 and 80 years. 3. Diagnosis of early-stage esophageal squamous cell carcinoma or precancerous lesions, with an elective ESD procedure planned. 4. Ability and willingness to adhere to the follow-up schedule, report symptoms accurately, and complete all required questionnaires.
Exclusion criteria
Exclusion criteria: 1. Severe dysfunction of major organs (e.g., heart, brain, lungs, liver, or kidneys). 2. Presence of multiple lesions requiring ESD. 3. History of prior thoracic or abdominal surgery. 4. Active preoperative infection (e.g., pneumonia, upper respiratory infection, urinary tract infection). 5. Pregnancy or lactation. 6. Severe coagulation disorders. 7. Any other condition deemed by the investigators to make the patient unsuitable for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score on the Numerical Rating Scale (NRS) at 6 hours post-ESD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of complications within 4 weeks post-ESD; | — |
Countries
China
Contacts
Public ContactFangyu Wang
Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University
Outcome results
None listed