Esophageal stricture
Conditions
Interventions
observation group:Radioactive cutting
Intervention group:Non-radial incision
Sponsors
Cancer Hospital, Chongqing University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age range: 18 to 80 years old. Physical condition should be able to tolerate endoscopic treatment and related examination and follow-up. Those diagnosed with benign esophageal stenosis based on medical history, clinical manifestations, gastroscopy, and imaging examinations (such as esophageal angiography, CT, etc.);patients with esophageal stenosis accompanied by symptoms such as dysphagia that affect their normal eating or quality of life;complete preoperative examinations, including biochemical tests, coagulation routine tests, and imaging examinations, etc., without any absolute contraindications for surgery;obtain written consent, voluntarily participate in this study and follow the requirements of the research protocol.
Exclusion criteria
Exclusion criteria: 1.Patients with esophageal stenosis or suspected malignant transformation of stenotic lesions caused by malignant tumors;patients with severe cardiac or pulmonary dysfunction, abnormal coagulation function, or other systemic diseases that prevent endoscopic procedures;patients with a history of esophageal surgery and severely altered anatomical structures that affect endoscopic incision operations or assessment;pregnant, lactating, or women planning to get pregnant during the study period; 5.patients with concurrent severe esophageal diseases (such as esophageal diverticulum, active esophageal variceal rupture bleeding, etc.) that may interfere with the interpretation of study results;severe mental disorders;patients who were participating in another clinical trial before randomization;patients who are unable to participate in follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of improvement in esophageal stenosis 3 months after treatment (the re-stenosis rate 3 months after esophageal ESD);the alleviation of dysphagia, and the improvement in quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of complications; | — |
Countries
China
Contacts
Public ContactChen Weiqing
Cancer Hospital, Chongqing University
Outcome results
None listed