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Effect of different doses of tegileridine in prevention of traction reaction during cesarean section of scarred uterus

Effect of different doses of tegileridine in prevention of traction reaction during cesarean section of scarred uterus

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117869
Enrollment
Unknown
Registered
2026-01-29
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traction reaction during cesarean section

Interventions

Group T1:Tigecycline Fumarate Injection, 0.015 mg/kg, administered by intravenous infusion over 10 minutes.
Group T2:Tigecycline Fumarate Injection, 0.02 mg/kg, administered by intravenous infusion over 10 minutes.
Group T3:Tigecycline Fumarate Injection, 0.025 mg/kg, administered by intravenous infusion over 10 minutes.
Group C:20 mL of normal saline, administered by intravenous infusion over 10 minutes.

Sponsors

Guanyun people's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification I/II 2. Age 20–45 years 3. BMI 18.8–30.0 kg/m^2 4. Gestation 37–42 weeks

Exclusion criteria

Exclusion criteria: 1. Contraindications to neuraxial anesthesia 2. Accompanied by gestational hypertension 3. Hepatic or renal insufficiency 4. Accompanied by severe cardiopulmonary disease 5. Placenta previa 6. Intrauterine fetal distress 7. Allergy or intolerance to any study drug

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative traction reaction;

Secondary

MeasureTime frame
Incidence of intraoperative shivering;Ramsay score;Satisfaction score after surgery;Occurrence of adverse reactionsrelated to tegileridine;Hemodynamic indices at special moments in the perioperative period;

Countries

China

Contacts

Public ContactQian Long

Guanyun people's Hospital

xqianlong@126.com+86 152 5124 5520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026