Acetaminophen-induced acute liver injuryAcetaminophen-induced acute liver injury
Conditions
Interventions
Healthy control group and AILI patient group:None
Sponsors
Huzhou Center Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.The patient clearly suffered from acute liver damage due to excessive intake of APAP and was admitted to the hospital within 24 hours after the excessive intake of APAP. This meets the diagnostic criteria for acute drug-induced liver injury. 2.Age range: 18 - 60 years old; 3.Agree to this experiment and sign the consent form;
Exclusion criteria
Exclusion criteria: 1.Does not meet the above diagnostic criteria and the inclusion criteria; 2.Recently, other medications that may affect the assessment of liver damage have been used, or other liver diseases such as viral hepatitis, alcoholic liver disease, and autoimmune liver disease have been concurrently present. 3.Merge patients with other primary diseases such as cardiovascular and cerebrovascular diseases, liver diseases, kidney diseases and hematological disorders; 4.Women during pregnancy or lactation period;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood test indicators(AST, ALT, ALP, TBil, INR, WBC, CRP, PCT, GCSF); | — |
Countries
China
Contacts
Public ContactZhang Yuwei
Huzhou Center Hospital
Outcome results
None listed