Reactive versus proactive symptom management based on patient-reported outcomes after lung cancer surgery: a multicenter, randomized controlled clinical trial (RESPONSE)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600117865

Enrollment

Unknown

Registered

2026-01-29

Start date

2026-02-05

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

PRO reactive symptom management group:Symptom early warning information is sent to the patient, and the patient proactively contacts the doctor for intervention (such as consultation, medication guida

PRO proactive symptom management:Symptom warning information is sent to the doctor, who will proactively contact the patient within 24 hours for intervention (such as education, medication guidance, a

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age>=18 years old; 2.Having undergone lung resection with histologically confirmed primary lung cancer, and are planned for discharge; 3.Having a smartphone or tablet with internet access at any time;

Exclusion criteria

Exclusion criteria: 1.Unable to understand the study content; 2.Participation in any other interventional study involving PRO reporting;

Design outcomes

Primary

Measure	Time frame
Target symptom score within 4 weeks of discharge;	—

Secondary

Measure	Time frame
Threshold event of symptoms at 4 weeks post-discharge;Functional score at 4 weeks post-discharge;Complications within 4 weeks post-discharge;Number of healthcare providers interventions;Duration of healthcare providers interventions;Physician acceptability;Patient satisfaction;Safety indicators (including: adverse events, long-term symptoms and functional scores);Long-term outcomes and functional score;	—

Measure

Time frame

Threshold event of symptoms at 4 weeks post-discharge;Functional score at 4 weeks post-discharge;Complications within 4 weeks post-discharge;Number of healthcare providers interventions;Duration of healthcare providers interventions;Physician acceptability;Patient satisfaction;Safety indicators (including: adverse events, long-term symptoms and functional scores);Long-term outcomes and functional score;

—

Countries

China

Contacts

Public ContactDai Wei

Sichuan Cancer Hospital

davii-i@126.com+86 28 85420367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026