Postoperative Pain Following Pectus Excavatum Repair in Pediatric Patients
Conditions
Interventions
Liposomal Bupivacaine Intercostal Nerve Block (ICB Group):The patient is placed in the lateral position. Usually, the 6th to 7th intercostal nerve is blocked, covering the upper and lower two rib spac
Ropivacaine with Dexamethasone Paravertebral Nerve Block Group (TPVB Group) :The patient was placed in the lateral position. The spinous process of the 5th thoracic vertebra was identified using ultr
Sponsors
West China Tianfu Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Age: 12 - 18 years old; 2. Elective for funnel chest NUSS surgery; 3. ASA: I - III grade; 4. Guardian signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Contraindications for regional nerve block (including coagulation disorders, allergy to local anesthetics, anatomical abnormalities, systemic infection, or infection at the injection site) 2. Guardian refusal or when the researcher deems it inappropriate to include in this study 3. Emergency surgery or reoperation patients 4. Postoperative ICU admission for continued supportive treatment 5. Already participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean NRS Resting Pain Score at 72 Hours Postoperatively Following NUSS Procedure for Pectus Excavatum; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting and Movement-Evoked NRS Pain Scores at 1, 12, 24, 48, and 72 Hours Postoperatively;Total Analgesic Consumption Within 24 and 48 Hours Postoperatively;Plasma Concentrations of Liposomal Bupivacaine at 10min, 30min, 60min, and 24h Post?injection;Time to First Request for Analgesia;Time to First Ambulation;Total Opioid Consumption via Patient-Controlled Analgesia (PCA) Pump and Number of PCA Demands;Total Analgesic Consumption Within 72 Hours;Length of Hospital Stay and Total Hospitalization Costs; | — |
Countries
China
Contacts
Public ContactDongjiao Wu
Sichuan University West China Tianfu Hospital
Outcome results
None listed