Dry eye caused by prolonged wear of orthokeratology lenses
Conditions
Interventions
experimental group:Gyogepipronate Sulfate Eye Drops
control group:Provide sodium hyaluronate eye drops
Sponsors
Hebei Eye Hospital
Eligibility
Sex/Gender
All
Age
8 Years to 16 Years
Inclusion criteria
Inclusion criteria: 1.Ages 8 to 16 years old; 2.The subjects have worn orthokeratology lenses for at least one year, and they did not have dry eye when they first wore orthokeratology lenses. 3.Mild dry eye: Any one of the following signs:5 seconds < FBUT < 10 seconds ; 5 mm/5 min<= Schirmer I <= 10 mm/5 min without surface anesthesia ; TMH < 0.2 mm; 1 to 5 corneal fluorescein staining points Plus any one of the following symptoms Subjective symptoms such as dryness, foreign body sensation, burning sensation, fatigue, discomfort, and fluctuating vision in the eyes.
Exclusion criteria
Exclusion criteria: 1.Having other eye diseases besides dry eye syndrome; 2.Having other systemic diseases that may affect the ocular surface; 3.The subjects had received any dry eye treatment within 14 days prior to enrollment; 4.The subject has undergone other eye surgeries.; 5.Refusal to sign the informed consent form; 6.Unable to cooperate with the examination for an extended period of time;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non-invasive tear film break-up time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index (OSDI-6) score;Meibomian gland score;Tear secretion;Uniformity of lipid layer distribution, color, and thickness;The number of corneal staining points;Non-invasive tear meniscus height; | — |
Countries
China
Contacts
Public ContactLonghui Han
Hebei Eye Hospital
Outcome results
None listed