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Efficacy and Safety Evaluation of Long-Pulse 1064 nm Laser Therapy for Foreign Body Reactions Following Injection

Efficacy and Safety Evaluation of Long-Pulse 1064nm Nd:YAG Laser Therapy for Foreign Body Reactions Following Low-Molecular-Weight Hyaluronic Acid Injections

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117815
Enrollment
Unknown
Registered
2026-01-29
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

multiple nodular foreign body reaction

Interventions

Long-pulse 1064nm Nd:YAG laser treatment group:None

Sponsors

The First Affiliated Hospital of Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: History of receiving HA or its complex injections, presenting with pronounced post-injection foreign body reactions, clinically diagnosed as post-HA injection foreign body reactions, and having undergone long-pulse 1064nm Nd:YAG laser treatment; Patients aged 18-60 years.

Exclusion criteria

Exclusion criteria: Severe hypertension (systolic/diastolic blood pressure >=180/120 mmHg), diabetes (fasting blood glucose >=126 mg/dL or HbA1c >=6.5%), renal failure (eGFR 2.0 mg/dL), history of malignancy, and patients who have received systemic or local glucocorticoid injections within the past month.

Design outcomes

Primary

MeasureTime frame
Number of treatments;recovery time;onset time;treatment interval;Side effects;—

Countries

China

Contacts

Public ContactZhang Qiguo

The First Affiliated Hospital of Xiamen University

zqgdreamer@163.com+86 572 213 7441

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026