vitamin K deficiency bleeding
Conditions
Interventions
Oral Vitamin K1 Supplement Group:NA
No oral vitamin K1 supplementation group:NA
Sponsors
The Third Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
No minimum to 0.3 Years
Inclusion criteria
Inclusion criteria: (1) Newborns delivered at each center; (2) Complete case records (including maternal pregnancy history and newborn birth information); (3) Informed consent from legal guardians.
Exclusion criteria
Exclusion criteria: (1) Mothers with psychiatric disorders, autoimmune diseases, bleeding disorders, tuberculosis, unclear pregnancy history, or long-term use of psychiatric medications, anticoagulants, hormonal drugs, or anti-tuberculosis drugs; (2) Mothers with a history of transfusion of plasma, cryoprecipitate, or fibrinogen complex within one month prior to delivery; (3) Newborns with life-threatening congenital malformations; (4) The newborn has chromosomal/genetic disorders or inherited metabolic diseases; (5) The newborn has thrombocytopenia or coagulation abnormalities due to severe hemangiomas, immunodeficiency, or other conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VitK1; | — |
Secondary
| Measure | Time frame |
|---|---|
| protein induced by vitamin K absence or antagonist-II; | — |
Countries
China
Contacts
Public ContactHuifang Dong
The Third Affiliated Hospital of Zhengzhou University
Outcome results
None listed