Knee Arthroplasty
Conditions
Interventions
0.2% Ropivacaine combined with Sufentanil group:0.2% ropivacaine combined with 0.5 µg/ml sufentanil, totaling 20 ml
0.1% ropivacaine combined with 4 µg/kg hydromorphone group:A total of 20 ml of 0.1% ropivacaine combined with 4 µg/kg hydromorphone was administered via femoral nerve block anesthesia on the operative
0.15% ropivacaine combined with 4 µg/kg hydromorphone group:A total of 20 ml of 0.15% ropivacaine combined with 4 µg/kg hydromorphone was administered via femoral nerve block anesthesia on the operati
0.2% ropivacaine combined with 4 µg/kg hydromorphone group:A total of 20 ml of 0.2% ropivacaine combined with 4 µg/kg hydromorphone was administered via femoral nerve block anesthesia on the operative
Sponsors
Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University),
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: 160 patients scheduled for knee arthroplasty were recruited for this study. The inclusion criteria were as follows: (1) Age 20–75 years; (2) patients classified as American Society of Anesthesiologists (ASA) physical status I–II; (3) BMI 20–25 kg/m^²; (4) Scheduled for elective unilateral knee arthroplasty; (5) Provided informed consent and completed baseline assessment.
Exclusion criteria
Exclusion criteria: (1) Presence of infection/hematoma at the femoral nerve puncture site, or peripheral neurological or neuromuscular diseases; (2) Refusal of nerve block; (3) Allergy to the study drugs; (4) Coagulation dysfunction; (5) Psychiatric disorders, and cognitive or language communication impairments; (6) Long-term use of analgesics, corticosteroids, or psychotropic drugs; (7) Inability to cooperate in completing the scales used in the study; (8) Poor diffusion of local anesthetics observed on ultrasound imaging; (9) Other conditions deemed by the investigator as unsuitable for participation in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain (visual analog scale, VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Rescue Analgesia Requirements;Complications;first time of analgesic;Muscle strength score of the lower limb on the operative side; | — |
Countries
China
Contacts
Public ContactGao Wei
Hainan General Hospital
Outcome results
None listed