Bilioenteric anastomotic strictures
Conditions
Interventions
PTCS group:Dilation of the anastomosis using a covered enteral stent via percutaneous transhepatic cholangioscopy (PTCS) in patients with bilioenteric anastomotic stricture.
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Previously underwent Roux-en-Y choledochojejunostomy; 2. The patient is diagnosed with benign stricture at the biliary-enteric anastomosis. The diagnosis is based on preoperative MRCP and intraoperative cholangiography or direct endoscopic visualization showing biliary stricture, combined with clinical symptoms such as jaundice, fever, abdominal pain, liver function abnormalities including elevated bilirubin and alkaline phosphatase, and abdominal ultrasound indicating bile duct dilation; 3. Age between 18 and 85 years; 4. General condition is good, without significant organic disease or functional impairment, able to tolerate general anesthesia; 5. Preoperative liver function is Child-Pugh class A or B; 6. The patient and family are informed and agree to PTCS treatment for the biliary stricture.
Exclusion criteria
Exclusion criteria: 1. Patients with acute biliary tract infection requiring emergency surgery; 2. Patients with absolute contraindications to PTCS/ERCP; 3. Pregnant or breastfeeding women; 4. Severe coagulation disorders: any of the following abnormalities – International Normalized Ratio (INR) >= 1.5, prothrombin time > 17 s, or platelet count <= 50×10^9/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical success rate;Perioperative mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital stay;Duration of the operation;Survival rate;surgical complication;Technical success rate;Recurrence rate of stenosis; | — |
Countries
China
Contacts
Public ContactRongxing Zhou
West China Hospital, Sichuan University
Outcome results
None listed