Deliration
Conditions
Interventions
experimental group:Preoperative transauricular vagus nerve stimulation for 20 minutes
control group:Wear an auricular vagus nerve stimulator without performing stimulation
Sponsors
Suzhou Hospital Affiliated to Nanjing Medical School (Suzhou Science and Technology City Hospital)
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1 Patients scheduled for elective hip surgery (including femoral neck, femoral head, intertrochanteric or subtrochanteric fractures, etc.); 2 Age >= 65 years; 3 ASA (American Society of Anesthesiologists) class II-III. 4 Edmondton frailty scale (REFS) screening for frailty, score =6 points.
Exclusion criteria
Exclusion criteria: 1 Multiple trauma or fractures, visual, speech, or hearing impairments, or neuropsychiatric disorders rendering evaluation or trial participation impossible; 2 Coagulation dysfunction; 3 History of severe cardiovascular or cerebrovascular diseases; 4 Sinus bradycardia or atrioventricular block; 5 Refusal to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of delirium within 3 days postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of delirium within 7 days postoperatively;The SedLine electroencephalogram (EEG) data were analyzed by extracting the data and inputting it into the Masimo Trace? Analysis and Reporting Tool software. The analysis included calculating the average PSI value, left and right lateralized spectral edge frequency (SEF) values, and burst suppression duration.;QoR-15 score;IL-6;TNF-a;visual analog scale; | — |
Countries
China
Contacts
Public ContactLI CHEN GUANG
Suzhou Hospital Affiliated to Nanjing Medical School (Suzhou Science and Technology City Hospital)
Outcome results
None listed