Painless Gastroenteroscopy
Conditions
Interventions
SD group/A group:Remimazolam was administered using the biased coin method.
NS group/C group:Remimazolam was administered using the biased coin method.
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 60 years 2.ASA physical status I or II 3.Body mass index (BMI) between 18 and 28 kg/m^² 4.Scheduled to undergo painless gastroenteroscopy
Exclusion criteria
Exclusion criteria: 1.Pregnant or breastfeeding women, or those with a pregnancy plan within the next 3 months 2.Contraindications or allergic reactions to benzodiazepines, propofol, opioids, or any components of these drugs 3.Significant preoperative respiratory or circulatory dysfunction (e.g., acute upper respiratory tract infection, acute asthma attack, acute exacerbation of chronic obstructive pulmonary disease, respiratory failure, uncontrolled severe hypertension, heart failure) 4.Severe hepatic dysfunction or renal insufficiency 5.History of schizophrenia, severe depression, or cognitive impairment 6.Sleep disorders or long-term use of sedative or analgesic medications 7.Inability to communicate or cooperate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the 90% effective dose (ED90) of remimazolam; | — |
Secondary
| Measure | Time frame |
|---|---|
| Full alert time;Total dose of remimazolam;Awakening time; | — |
Countries
China
Contacts
Public ContactDan cheng
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed