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Clinical efficacy of rPMS combined with rTMS in the treatment of post-stroke hemiplegic shoulder pain and the study of peripheral central synergistic regulation mechanism

Clinical efficacy of rPMS combined with rTMS in the treatment of post-stroke hemiplegic shoulder pain and the study of peripheral central synergistic regulation mechanism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117741
Enrollment
Unknown
Registered
2026-01-28
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemiplegic shoulder pain

Interventions

Control Group:Routine limb function training: including passive range of motion training for the shoulder joint (20 minutes/session), and inter site electrotherapy for painful areas (15 minutes/sessio
Combined Group:On the basis of the control group, rPMS and rTMS treatments were given. The target of rPMS stimulation was the projection point of the suprascapular foramen on the affected side of SSN
RTMS stimulation target: M1 area on the affected side (located using MRI navigation), frequency: 10Hz, intensity: 80% RMT, pulse count: 1000 pulses per time (5 seconds on, 55 seconds off). About 20 mi
rPMS Group:On the basis of the control group, rPMS treatment was given. The stimulation target was the surface projection point of the suprascapular foramen on the affected side of the SSN (1cm above
rTMS Group:Based on the control group, rTMS treatment was given. The stimulation target was the M1 area on the affected side (MRI navigation positioning), frequency: 10Hz, intensity: 80% RMT, pulse co

Sponsors

Jiaxing Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for stroke in the "2019 Diagnostic Guidelines for Major Cerebrovascular Diseases in China", confirmed by CT or MRI, first onset; 2. stable vital signs, good blood pressure control, and no other restrictions on activity comorbidities; 3. disease duration= 23 points, able to cooperate with rehabilitation training; 6: sign informed consent form.

Exclusion criteria

Exclusion criteria: 1. Individuals who are allergic to magnetic stimulation, have local skin damage, or have metal internal fixation implants in the shoulder joint; 2. Installing pacemakers, defibrillators, aneurysm clips (non titanium alloy), cochlear implants, intracranial metal implants, etc. inside the body; 3. Patients with a history of shoulder joint injury or surgery, or those with shoulder pain caused by other diseases such as shoulder dislocation, severe rotator cuff injury, etc; 4. Previous history of epileptic seizures or family history of epilepsy inheritance; 5. Patients with important organ diseases such as heart, lung, kidney, or malignant tumors; 6. The MRI examination cannot be completed due to fear of confinement, discomfort with noise, etc; 7. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Numeric rating scale, NRS;Passive range of motion, PROM;Regional homogeneity, ReHo;Resting motor threshold, RMT;Amplitude of low-frequency fluctuation, ALFF;Fraction amplitude of low-frequency fluctuation, fALFF;

Secondary

MeasureTime frame
Fugl-Meyer assessment scale-upper extremity, FM-UE;Modified Ashworth scale, MAS;

Countries

China

Contacts

Public ContactMa Lianjie

Jiaxing Second Hospital

mljqbyxbx@163.com+86 153 5144 1431

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026