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The application of esketamine in patients at high risk of nausea and vomiting during surgery

The application of esketamine in patients at high risk of nausea and vomiting during surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117711
Enrollment
Unknown
Registered
2026-01-28
Start date
2026-01-28
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients at high risk of nausea and vomiting

Interventions

Group A:Group A: Esmetomidone 0.2mg/kg, sufentanil 0.3ug/kg, propofol 0.4mg/kg, cisatracurium 0.2mg/kg
Group B:Group B: sufentanil 0.5ug/kg, propofol 0.4mg/kg, cisatracurium 0.2mg/kg

Sponsors

Anesthesiology Department of Ningxia Uyghur Autonomous Region People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Female patients who do not smoke. 2. Undergoing laparoscopic hysterectomy. 3. ASA classification I-III. 4. Mentally and intellectually normal, able to communicate normally. 5. Voluntarily signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to anesthesia. 2. Patients with severe organ dysfunction. 3. Patients with central nervous system disorders. 4. Patients with respiratory system disorders. 5. Patients with opioid dependence. 6. Pregnant or lactating women. 7. Patients who refuse to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
The occurrence of postoperative nausea and vomiting;—

Countries

China

Contacts

Public ContactWuzhaozhao

Ningxia Uygur Autonomous Region People's Hospital

958602650@qq.com+86 159 0967 5605

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026