Regulate the imbalance of the microbiota
Conditions
Interventions
Add inactivated probiotic hygiene products group :Use FREEMORE probiotic feminine hygiene products containing inactivated L. acidophilus LA88 and L. plantarum N13.
Control group of hygiene products without added inactivated probiotics:Use FREEMORE feminine hygiene products
Sponsors
The First Affiliated Hospital of Henan University of Science and Technology
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Female, aged 18-40, with sexual life, regular menstrual cycle (menstruation lasts about 5-7 days, cycle is approximately 28-31 days) 2. White discharge grade 2-4, female with vaginal flora imbalance (7-item vaginal microecological test) 3. The patient signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with systemic diseases or those who are currently receiving (anti-tumor, antibiotic, hormone, etc.) drug treatment within the last month; 2. Patients with vaginal diseases who are undergoing treatment in relevant departments and have been determined to affect the efficacy evaluation of this project; 3. Those who are allergic to the components of the inactivated probiotic sanitary products used in this trial; 4. Researchers who have participated in clinical trial studies related to this project within the last month; 5. Pregnant or lactating women or those with a recent pregnancy plan; 6. Those who have discontinued the test samples, whose efficacy cannot be determined or whose data is incomplete; 7. Other research participants deemed unsuitable for participation by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Routine examination of vaginal discharge + 7-inclusive vaginal microecological test;Vaginal microbiome sequencing;questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vaginal inflammatory factors; | — |
Countries
China
Contacts
Public ContactYing Wu
The First Affiliated Hospital of Henan University of Science and Technology
Outcome results
None listed