None listed
Conditions
Interventions
Group D2:Cleavage-Stage Embryo D2 Transfer
Group D3:Cleavage-Stage Embryo D3 Transfer
Sponsors
Women’s Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Ages: females 20-45 years, males 22-55 years; 2.BMI:female 18.5-30 kg/m^2; 3.Treatment Type: Planned to undergo IVF or ICSI treatment, with ovarian stimulation protocol, an antagonist protocol, or long protocol in this cycle; 4.Number of fertilized eggs: Patients with >=1 prior IVF/ICSI cycle(s) in which no usable embryos were obtained on Day 3 (defined as >=6 cells, fragmentation =7 mm with a Type A or Type B morphology, and with no intrauterine fluid; 6.Informed Consent: Patients sign a written informed consent form before oocyte retrieval and receive treatment at the participating institutions.
Exclusion criteria
Exclusion criteria: 1.PGT cycle, Donor sperm/oocyte cycle, TESE/ Micro-TESE cycle; 2.Anatomical abnormalities: Septate uterus, bicornuate uterus, unicornuate uterus, or didelphic uterus; endometrial Lesions: Untreated endometrial polyps, adenomyosis, moderate to severe intrauterine adhesions, submucosal uterine fibroids, or intramural fibroids. 3.A history of recurrent miscarriage of Recurrent Implantation Failure or Recurrent Miscarriage; 4.Uncontrolled hypertension, type 2 diabetes mellitus, hepatic insufficiency, renal insufficiency, severe anemia, history of thromboembolism; Hydrosalpinx, active pelvic inflammatory disease; 5.Others: Hypersensitivity to ovulation induction medications, participation in other clinical trials within the past 6 months, or being deemed unsuitable for enrollment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rate in the first embryo transfer cycle; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pregnancy rate in the first embryo transfer cycle;Multiple Pregnancy Rate;Usable Embryo Rate;OHSS rate;Embryo Freezing Rate;Biochemical pregnancy rate;Implantation rate;Early miscarriage rate (before 12 weeks of gestation);Cost per live birth; | — |
Countries
China
Contacts
Public ContactHuang Hefeng
Women’s Hospital, Zhejiang University School of Medicine
Outcome results
None listed