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The clinical effect of Chlorine Dioxide Mouthwash in Alleviating gingivitis and its antibacterial mechanism

The clinical effect of Chlorine Dioxide Mouthwash in Alleviating gingivitis and its antibacterial mechanism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117686
Enrollment
Unknown
Registered
2026-01-27
Start date
2024-06-26
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis

Interventions

Experimental group:USE Chlorine Dioxide Mouthwash
Control group: use Chlorhexidine mouthwash

Sponsors

college of Stomatology,Xi'an Jiaotong University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Good overall health condition, with more than 18 teeth available for clinical examination; 2.Be at least 18 years old; 3.PI>=1.5 and GI>=1; 4.Not participating in the same type of clinical trials simultaneously; (5) Be informed and give consent to the test content and process, and be able to cooperate with the test process.

Exclusion criteria

Exclusion criteria: 1.There is a history of allergy to the ingredients of the mouthwash used in the experiment; 2.Having used antibiotics within two weeks prior to participating in the study; 3.Open caries reaching subgingival; 4.Women who are pregnant or breastfeeding, or who have plans to conceive during the trial period; 5.There are orthodontic appliances, implants, partial removable dentures or orthodontic retainers in the oral cavity; 6.Have systemic diseases throughout the body.

Design outcomes

Primary

MeasureTime frame
Gingival Index;Plaque Index;Sulcus Bleeding Index;

Countries

China

Contacts

Public ContactRuizhe Huang

college of Stomatology,Xi'an Jiaotong University.

huangrzh@mail.xjtu.edu.cn+86 137 7202 8359

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026