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Comparison of the safety and efficacy of oliceridine combined with propofol versus sufentanil combined with propofol for hysteroscopic surgery

Comparison of the safety and efficacy of oliceridine combined with propofol versus sufentanil combined with propofol for hysteroscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117672
Enrollment
Unknown
Registered
2026-01-27
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscopic surgery

Interventions

Oliceridine group:Intravenous injection of oliceridine at a dose of 20 µg/kg
Sufentanil Group:Intravenous injection of sufentanil at a dose of 0.1 µg/kg

Sponsors

Chinese People's Liberation Army Northern Theater Command General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 Scheduled to undergo hysteroscopic surgery under general anesthesia; 2 Aged 18–60 years; 3 American Society of Anesthesiologists (ASA) physical status classification I–II; 4 Body Mass Index (BMI) 18.5–28.0 kg/m^2.

Exclusion criteria

Exclusion criteria: 1 Patients with severe hepatic or renal insufficiency, or coagulation disorders. 2 Patients with cardiopulmonary diseases (such as hypertension, arrhythmia, coronary heart disease, bradycardia, asthma, etc.). 3 Patients with a history of moderate to severe motion sickness or a history of severe nausea and vomiting. 4 Patients with a history of mental illness or cognitive impairment. 5 Patients with allergies or contraindications to the drugs planned for anesthesia. 6 Patients assessed preoperatively as having a difficult airway.

Design outcomes

Primary

MeasureTime frame
Incidence of respiratory depression;

Secondary

MeasureTime frame
Anesthesia-Related Time;Dosage of Propofol;Incidence of other adverse reactions;Vital sign;

Countries

China

Contacts

Public ContactHuijuan Cao

The General Hospital of the PLA Northern Theater Command

caohuijuan1212@sina.com+86 133 0988 0882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026