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Predictive Value of Short-term Changes in Heart Rate Variability Combined with Systemic Inflammation Response Index for Short-term Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome

Predictive Value of Short-term Changes in Heart Rate Variability Combined with Systemic Inflammation Response Index for Short-term Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117639
Enrollment
Unknown
Registered
2026-01-27
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Interventions

Experimental group (MACE group):None
Control group (non-MACE group):None

Sponsors

Yuebei People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Meet the diagnostic criteria for acute coronary syndrome (ACS); confirmed as ACS patients through medical history verification, electrocardiographic examination, and detection of serum myocardial enzyme markers.

Exclusion criteria

Exclusion criteria: 1.Severe cardiac insufficiency; 2.Patients with atrial fibrillation; 3.Patients with malignant arrhythmias; 4.After pacemaker implantation; 5.Presence of infectious diseases; 6. Recent history of taking antibiotic drugs; 7. Those who have recently taken hormone drugs and immunosuppressants.

Design outcomes

Primary

MeasureTime frame
heart rate variability, HRV;Systemic Inflammation Response Index, SIRI;Major adverse cardiovascular events (MACE);—

Secondary

MeasureTime frame
Cardiac troponin (cTn);Creatine kinase isoenzyme MB (CK-MB);N-terminal pro-brain natriuretic peptide (NT-proBNP);Left ventricular ejection fraction (LVEF);high-sensitivity C-reactive protein (hs-CRP);—

Countries

China

Contacts

Public ContactXiangyang Liu

Yuebei People’s Hospital

longliu0714@sina.com+86 751 6913731

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026