Osteoporosis
Conditions
Interventions
Healthy Control Group:None
Sponsors
The Ethics Committee of the First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Osteoporosis Group 1. Age >= 18 years, either sex; 2. Osteoporosis group: Diagnosed with osteoporosis according to DXA bone mineral density criteria (T-score -1.0); 3. No history of fracture and no history of metabolic bone disease; 4. Voluntarily participates in the study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: Osteoporosis Group 1. Suffering from severe liver or kidney dysfunction; 2. Suffering from other diseases affecting bone metabolism, such as hyperparathyroidism, malignant bone metastasis, or multiple myeloma; 3. Received drug treatment affecting bone metabolism within the past 3 months. Healthy Control Group 1. Suffering from severe liver or kidney dysfunction; 2. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone Metabolism Markers;Peripheral blood was used to determine ß-CTX, TPINP and 25-OH VD;The area under the curve (AUC) of each marker under the three sample types (serum, peripheral blood, and dried blood smear) and the sensitivity and specificity at their respective optimal cut-off values; | — |
Countries
China
Contacts
Public ContactYang Huiling
The First Affiliated Hospital of Soochow University
Outcome results
None listed