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Study on the Preventive Effect of Transcranial Direct Current Stimulation on Early Postoperative Nausea and vomiting (PONV) in Patients Undergoing Thyroid Surgery

Study on the Preventive Effect of Transcranial Direct Current Stimulation on Early Postoperative Nausea and vomiting (PONV) in Patients Undergoing Thyroid Surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117628
Enrollment
Unknown
Registered
2026-01-27
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Interventions

Trial group 1:For patients in Experimental Group 1, transcranial direct current stimulation was applied preoperatively, with the anode placed over the left dorsolateral prefrontal cortex and the catho
Trial group 2:Patients in Experimental Group 2 received preoperative sham transcranial direct current stimulation, with the anode placed over the left dorsolateral prefrontal cortex and the cathode pl

Sponsors

Longyan First Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 - 60. 2. ASA physical status ? - ?. 3. Patients scheduled for elective thyroid surgery.

Exclusion criteria

Exclusion criteria: 1.Patients who refuse to sign the consent form or are unable to understand the questionnaire content; 2.Patients with neurological or psychiatric disorders, or a history thereof; 3.Patients with cranial or scalp injuries; 4.Patients with severe cardiovascular or cerebrovascular diseases; 5.Patients with severe hepatic or renal dysfunction; 6.Patients with severe respiratory system diseases; 7.Patients with metal implants in the body; 8.Patients with chronic pain who have long-term use of analgesics or psychiatric medications (including opioids, non-steroidal anti-inflammatory drugs, sedatives, and antidepressants); 9.Patients with severe arrhythmias or neuromuscular system diseases; 10.Patients on long-term use of long-acting antiemetics, emetics, opioids, or corticosteroids; 11.Patients with a history of motion sickness or postoperative nausea and vomiting (PONV); 12.Patients with other conditions that may present with nausea or vomiting, such as hepatitis or gastric ulcers; 13.Any patient currently experiencing vomiting or who has taken antiemetics or steroids within 72 hours prior to surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of PONV within 24 hours after thyroid surgery;

Secondary

MeasureTime frame
Severity and frequency of postoperative nausea and/or vomiting within 72 hours;Time to first onset of PONV;The Numerical Rating Scale (NRS) was used to score the pain during rest and exercise 24 hours after the operation;Need for rescue antiemetic;Opioid dosage;

Countries

China

Contacts

Public ContactLi Shihai

Longyan First Affiliated Hospital of Fujian Medical University

lysylsh01@163.com+86 139 5900 2329

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026