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Effects of Exercise Intervention Strategies on Lower Limb Pain, Function, and Biomechanical Characteristics in Patients with Concomitant Chronic Ankle Instability and Patellofemoral Pain

Effects of Exercise Intervention Strategies on Lower Limb Pain, Function, and Biomechanical Characteristics in Patients with Concomitant Chronic Ankle Instability and Patellofemoral Pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600117626
Enrollment
Unknown
Registered
2026-01-27
Start date
2026-01-31
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic ankle instability

Interventions

Sponsors

East China Normal University, College of Physical Education and Health
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-45 years old; 2. Meeting the diagnostic criteria for CAI: a history of at least one ankle sprain, with the first sprain occurring more than 12 months ago; experiencing recurrent episodes of the ankle giving way, or actual occurrences, or persistent symptoms such as pain, swelling, limited mobility, or weakness; CAIT score < 24 points; 3. Meeting the diagnostic criteria for PFP: pain located behind or around the patella; pain behind or around the patella can be reproduced during patellofemoral joint loading activities such as squatting, climbing stairs, or prolonged sitting with knees bent; excluding other conditions that may cause anterior knee pain, such as patellar tendinopathy, patellofemoral instability, or knee osteoarthritis; AKPS score < 83 points; 4. Able to understand and sign the informed consent form; 5. Able to follow the study protocol and complete all assessments and training.

Exclusion criteria

Exclusion criteria: 1. History of lower limb surgery within the past 6 months; 2. Combined with other musculoskeletal diseases affecting lower limb function (such as knee ligament or meniscus injury, hip joint disease, etc.); 3. Suffering from neurological diseases, rheumatic immune diseases, or other severe systemic diseases; 4. Having serious cardiovascular or respiratory diseases that are not suitable for exercise training; 5. Pregnant or breastfeeding women; 6. Received systematic physical therapy or rehabilitation training for CAI or PFP within the past 3 months; 7. Presence of significant lower limb structural deformities that affect biomechanical testing.

Design outcomes

Primary

MeasureTime frame
Subjective pain and functional outcomes;

Secondary

MeasureTime frame
Objective functional performance;Lower limb biomechanics and electromyographic indicators;

Countries

China

Contacts

Public ContactYouping Sun

East China Normal University, College of Physical Education and Health

sunyouping@163.com+86 13636335137

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026