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Multicenter Analysis of Cardiovascular Hemodynamics via in-silico engineering (MACHINE)

Multicenter Analysis of Cardiovascular Hemodynamics via in-silico engineering (MACHINE)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117589
Enrollment
Unknown
Registered
2026-01-26
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Aortic Aneurysm

Interventions

Observational group:None

Sponsors

The First Affiliated Hospital,Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age 50-90 years 2. Undergoing EVAR for infrarenal true abdominal aortic aneurysm 3. Complete preoperative CTA imaging data available 4. At least two postoperative follow-up records with complete imaging data available (T1 = 6 months)

Exclusion criteria

Exclusion criteria: 1. Ruptured abdominal aortic aneurysm 2. Infected abdominal aortic aneurysm 3. Inflammatory abdominal aortic aneurysm 4. Involvement of visceral branch reconstruction or iliac branch reconstruction 5. Detection of other types of endoleaks during postoperative follow-up 6. Presence of other severe comorbidities postoperatively 7. Severe, rare vascular malformations 8. Diagnosed connective tissue disease 9. Preoperative thrombotic occlusion of the inferior mesenteric artery 10. Intraoperative prophylactic interventions for endoleak, such as coil embolization or fibrin glue injection 11. Poor quality of preoperative or postoperative imaging, inadequate for 3D model reconstruction and subsequent CFD computations

Design outcomes

Primary

MeasureTime frame
Type II Endoleak (T2EL) detected on follow-up 6 to 12 months after EVAR.;

Secondary

MeasureTime frame
Type II Endoleak (T2EL) detected at any time point during follow-up within 12 months after EVAR.;Average flow and peak flow in the superior mesenteric artery and internal iliac artery during the cardiac cycle;

Countries

China

Contacts

Public ContactYao Chen

The First Affiliated Hospital,Sun Yat-sen University

yaochen@mail.sysu.edu.cn+86 135 0150 4763

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026