Postoperative nausea and vomiting
Conditions
Interventions
Ciprofol group:Anesthesia induction: Intravenous remimazolam 0.4 mg/kg, cisatracurium besylate 0.2 mg/kg, sufentanil 0.2 µg/kg, and remifentanil TCI at 4–8 ng/ml, plus dexamethasone 5 mg.
Intraopera
Propofol group:Anesthesia induction: Intravenous propofol 2 mg/kg, cisatracurium besylate 0.2 mg/kg, sufentanil 0.2 µg/kg, remifentanil TCI at 4–8 ng/ml, and dexamethasone 5 mg.
Intraoperative maint
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-70 years old; 2.ASA:?~III; 3.Patients undergoing elective gynecological laparoscopic surgery and signing the trial informed consent form;
Exclusion criteria
Exclusion criteria: 1.Those who have used antiemetic drugs within 24 hours before surgery or have any symptoms of nausea or vomiting during the same period; 2.Alcoholics and illegal drug users; 3.Pregnancy or breastfeeding; 4.Illiterate, visually and hearing impaired patients; 5.Patients with severe liver and kidney dysfunction;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of nausea and vomiting within 24 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of first postoperative exhaust gas;QoR-15 score;Postoperative nausea and vomiting severity; | — |
Countries
China
Contacts
Public ContactChen Wenting
Southern Medical University Southern Hospital
Outcome results
None listed