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Measurement of blood flow reserve fraction based on coronary angiography images

Measurement of blood flow reserve fraction based on coronary angiography images

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117577
Enrollment
Unknown
Registered
2026-01-26
Start date
2025-04-20
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Interventions

Gold Standard:FFR is the "gold standard" for functional index interpretation (when the measured FFR value is =0.75 and =0.85, the preset limit for pressure shift is 0.02. When the measured FFR value i
Index test:Based on coronary angiography images, the fractional flow reserve at the coronary stenosis was calculated through three-dimensional vascular reconstruction and hemodynamic algorithms, witho

Sponsors

Changzhou Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The degree of stenosis of the target vessel lumen is visually assessed to be >=50% and =2 mm; 3. Two coronary angiographic images with projection angles differing by more than 25° are available to meet the requirements for 3D uFFR analysis.

Exclusion criteria

Exclusion criteria: 1. Lesions at the mouth of the vessel; 2. History of coronary artery bypass graft surgery; 3. Lumen narrowing caused by a myocardial bridge; 4. Poor quality of angiographic images, making vessel boundaries unclear or insufficient contrast agent filling.

Design outcomes

Primary

MeasureTime frame
2D manual uFFR results;

Secondary

MeasureTime frame
3D manual uFFR results;

Countries

China

Contacts

Public ContactHongjun Wang

Changzhou Cancer Hospital

whj120@163.com+86 519 69807726

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026