Central nervous system injury diseases, such as stroke, cerebral palsy, traumatic brain injury, spastic paralysis of the upper limbs during the recovery period of spinal cord injury patients
Conditions
Interventions
Control group:Peripheral nerve balancing
Intervention group:Peripheral Nerve Balancing + Rehabilitative Train
Sponsors
Beijing Bo'ai Hospital
Eligibility
Sex/Gender
All
Age
12 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients over 12 years old with stroke, cerebral palsy (hemiplegia, triple limb palsy, quadriple limb palsy), traumatic brain injury, cerebral tumor, cerebrovascular accident and other central nervous system injuries with limb spasticity or central spastic palsy develop spasticity of the upper limbs after one year and the degree of spasticity is unchanged in the last 3 months; 2. Spasticity state is not significantly improved or relapsed by conservative treatments (physical therapy, occupational therapy, medication, botulinum toxin injections, etc.); 3. Modified Ashworth Scale (MAS) >= grade 2 without upper limb deformity.
Exclusion criteria
Exclusion criteria: 1. severe mental or cognitive impairment, unable to cooperate with the rehabilitation training; 2. serious primary disease or poor general physical condition; 3. combined with severe irreversible muscle contracture and bone deformity; 4. contraindications to surgery or anesthesia; 5. long term oral anti-spasticity drugs such as baclofen, carbamazepine, etc. have not been discontinued.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surface electromyography;Modified Ashworth Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Range of motion;Fugl-Meyer Upper Extremity Scale;Simple test for evaluating hand function;Modified Barthel Index;Self-rating Anxiety Scale;Self-rating Depression Scale;Motor Evoked Potential;Task-Based Functional Magnetic Resonance Imaging;Electroencephalogram;Pinch test;Grip strength test;Shallow sensory assessment;Deep Sensory Assessment;Manual muscle test; | — |
Countries
China
Contacts
Public ContactLi Jun
Beijing Bo'ai Hospital
Outcome results
None listed