A Study on Expression Levels of Programmed Death-1 Protein (PD-1) in Peripheral Blood of Patients with Chronic Schizophrenia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600117562

Enrollment

Unknown

Registered

2026-01-26

Start date

2026-01-31

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Schizophrenia patient group:No

Healthy control group:No

Eligibility

Sex/Gender

All

Age

18 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1. Meeting the diagnostic criteria for schizophrenia according to the International Classification of Diseases, 10th Revision (ICD-10); 2. Right-handed; 3. Han Chinese ethnicity; 4. Aged 18–59 years.

Exclusion criteria

Exclusion criteria: 1. Comorbid with other psychiatric disorders; 2. History of severe allergies; 3. Accompanied by serious physical illnesses; 4. Inability to read or speak Chinese; 5. Intellectual disability; 6. Currently experiencing acute positive symptoms (PANSS positive subscale score > 28).

Design outcomes

Primary

Measure	Time frame
The plasma levels of PD-1, PD-L1, PD-L2, IL-10, TNF-a, IFN-?, and IL-6;Psychiatric symptoms ;cognitive function;social function;quality of life;	—

Countries

China

Contacts

Public ContactJinqiong Zhan

JiangXi Mental Health Center

415629958@qq.com+86 791 88176163

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026