Autism Spectrum Disorders
Conditions
Interventions
tACS-only intervention group:This protocol involved tACS stimulation exclusively, targeting the F3-F4 positions according to the EEG 10-20 system. The stimulation was administered at an intensity of 1
Combined tACS and neurofeedback intervention group:In addition to the tACS intervention, participants concurrently performed neurofeedback training tasks. This combined session lasted 30 minutes, was
Control group:Received no intervention
Sponsors
Chengdu Women and Children's Central Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for Autism Spectrum Disorder (ASD); 2. Aged between 3 and 12 years; 3. No history of central nervous system-acting medication use within the past 3 months; 4. Absence of head trauma history or metallic implants; 5. Ability to comply with procedures for both EEG and tACS stimulation.
Exclusion criteria
Exclusion criteria: 1. Evidence of a psychiatric disorder other than childhood neurodevelopmental disorders, as identified by the MINI International Neuropsychiatric Interview; 2. Use of any other medication affecting central nervous system function within the past two weeks; 3. History of other neurological disorders confirmed through rehabilitation department evaluation, physical examination, and auxiliary tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADOS-2 scale scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalogram;Aberrant Behavior Checklist (ABC) score, Social Responsiveness Scale (SRS) score, Frontal Lobe Function Assessment Scale score;Accuracy ang Reaction Time in behavioral tasks; | — |
Countries
China
Contacts
Public ContactZhou Wenzhi
Chengdu Women and Children's Central Hospital
Outcome results
None listed