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Exploring the Mechanisms and Precision Intervention Strategies for Antimicrobial Prescribing Behaviors Among Intensive Care Unit Physicians: A KAP-COM-B Integrated Framework Model from the Perspective of Cognitive Bias

Exploring the Mechanisms and Precision Intervention Strategies for Antimicrobial Prescribing Behaviors Among Intensive Care Unit Physicians: A KAP-COM-B Integrated Framework Model from the Perspective of Cognitive Bias

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117548
Enrollment
Unknown
Registered
2026-01-26
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial infection

Interventions

Case series:NA

Sponsors

Department of Pharmacy, The Second Affiliated Hospital of Xi’an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Doctor: (1) Possess the qualifications and authority to independently prescribe antibacterial drugs; (2) During the research period, at least 100 patients who met the inclusion criteria were managed to ensure the statistical reliability of the prescription data; (3) Be proficient in using VR devices and be willing to participate. 2. Patient: (1) Adult patients aged 18 or above; (2) Receive at least one type of antibacterial drug treatment during the ICU stay; (3) The length of stay in the ICU is more than 24 hours but less than 30 days; (4) Diagnosed with infectious diseases (with clear ICD-10 codes), including but not limited to sepsis, bacterial pneumonia, urinary tract infections, etc. (5) Only patients who have undergone postoperative prophylaxis, empirical treatment, or have been confirmed to be infected with pathogenic bacteria are included. The antibacterial drug treatment is determined by the critical care physician, and there are corresponding treatment guidelines available for rationality assessment.

Exclusion criteria

Exclusion criteria: 1.Doctor: (1) Not involved in the decision-making of antibacterial drug prescriptions for ICU patients or not involved in antibacterial drug treatment; (2) Incomplete or missing records of prescriptions and decision-making for antibacterial drugs; (3) Intern doctor. 2. Patient: (1) Only using antifungal or antiviral drugs; (2) Had received antibacterial drug treatment before being admitted to the ICU; (3) The use of antibacterial drugs only for gastric motility therapy (such as erythromycin); (4) Only use non-systemic antibacterial drugs (such as topical application, nebulized inhalation, bladder irrigation, etc.); (5) Changes in the attending physician during the ICU stay; (6) Due to reasons such as transfer within 72 hours, death or consciousness disorder, the observation of the four decision-making stages cannot be completed.

Design outcomes

Primary

MeasureTime frame
Comprehensive score for the rationality of antibacterial drug prescriptions;

Secondary

MeasureTime frame
The intensity of antibacterial drug use;Changes in the sensitivity of bacterial genera;The 28-day all-cause mortality rate of the patient;

Countries

China

Contacts

Public ContactYan Wang

The Second Affiliated Hospital of Xi’an Jiaotong University

wangyan0819@mail.xjtu.edu.cn+86 188 2978 8258

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026