Acute respiratory failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.Patients admitted to Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, between January 2019 and December 2024 and receiving non-invasive respiratory support; 3.Received non-invasive respiratory support for more than 2 hours, including non-invasive mechanical ventilation and high-flow oxygen therapy;
Exclusion criteria
Exclusion criteria: 1.Planned for invasive mechanical ventilation upon admission (e.g., post-cardiac arrest resuscitation, severe neuromuscular disease, or anticipated ventilation failure); 2.Restricted life-sustaining measures due to terminal illness or explicit treatment-limiting preferences; 3.Had already received invasive mechanical ventilation prior to non-invasive respiratory support; 4.Severe lack of clinical data preventing calculation of key variables (e.g., SpO2, FiO2, respiratory rate, airway pressure, etc.); 5.Pregnancy status (due to physiological changes that may affect oxygenation and respiratory mechanics, along with special ethical considerations); 6.Participation in other interventional clinical trials that may interfere with the assessment of the study endpoints;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ares Uner the Receier operating CharzeterstieCure,AJC; | — |
Countries
China
Contacts
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University