Perianal Pain
Conditions
Interventions
control group:Topical application of conventional analgesics postoperatively
experimental group A:Liposomal bupivacaine was injected locally into the perianal region postoperatively
experimental group B:Liposomal bupivacaine was injected locally into the perianal region postoperatively (Low dose).
experimental group D:Liposomal bupivacaine simultaneously injects into the perianal subcutaneous tissue and intersphincteric space postoperatively.
Blank control group:Normal saline was injected locally into the perianal region postoperatively.
experimental group C:Liposomal bupivacaine was administered locally into the anal sphincter space postoperatively.
Sponsors
The First People’s Hospital of Wenling
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with mixed hemorrhoids, anal fissure, anal fistula, or perianal abscess; 2. Meeting the surgical indications and undergoing standard surgical treatment; 3. Having good compliance, being willing to participate in the study and sign the informed consent form; 4. Aged 18-60 years old.
Exclusion criteria
Exclusion criteria: 1. Complicated with hypertension, diabetes mellitus, malignant tumors, or major diseases of the cardiovascular, hepatic, renal or other vital systems; 2. Those with severe postoperative complications; 3. Those allergic to the drugs in the project or failing to meet their indications; 4. Special populations (pregnant women, lactating women, patients with mental illness, critically ill patients, minors) or those with poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score;Postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stay;Rescue medication use;Wound healing time;Satisfaction degree; | — |
Countries
China
Contacts
Public ContactYinghao Jiang
The First People’s Hospital of Wenling
Outcome results
None listed