Herpes zoster
Conditions
Interventions
Combined Light Group:Compound light intervention
Red Light Group:Red light intervention
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.All eligible patients were diagnosed as herpes zoster by clinical diagnosis, with blisters, papules, erosions and ulcers in the skin lesions. The diagnostic criteria referred to the Second edition of Chinese Clinical Dermatology. 2.Patients with complete clinical data were >=60 years old; 3.Patients who have not used corticosteroids within 3 months; 4.No photosensitive disease or use of photosensitive drugs within 6 months; 5.Good compliance to complete treatment and follow-up;
Exclusion criteria
Exclusion criteria: 1.Patients with mental illness or critical illness, unable to effectively realize the reasonable expression of self-consciousness and effectively evaluate the efficacy and safety of treatment; 2.Pregnant or lactating women; 3.Patients or their family members disagreed with the research content or could not meet the relevant needs of research data collection. 4.Photosensitive people and photointolerant people;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to blister cessation;Time to crusting;Time to crust shedding;Change in VAS score before and after treatment;Time to pain resolution;Time to pain relief;Incidence rate of postherpetic neuralgia (PHN); | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in C-reactive protein (CRP) level before and after treatment;Change in absolute count of CD8+ T lymphocytes before and after treatment;Clinical efficacy after treatment;Change in absolute count of CD4+ T lymphocytes before and after treatment;Change in neuron-specific enolase (NSE) level before and after treatment;Change in erythrocyte sedimentation rate (ESR) level before and after treatment;Occurrence of adverse events during treatment;Change in DLQI score before and after treatment;Change in CD4+/CD8+ T lymphocyte ratio before and after treatment; | — |
Countries
China
Contacts
Public ContactXianwei Cao
The First Affiliated Hospital of Nanchang University
Outcome results
None listed