Hemifacial Spasm
Conditions
Interventions
Intervention Group:On the basis of standard postoperative treatment, 100 mg of hydrocortisone was administered via intravenous infusion at the initiation of anesthesia induction, and the administratio
Control group:An equal volume of saline was administered intravenously at the same time points as in the intervention group.
Sponsors
The Second People's Hospital of Liaocheng City
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Plan to undergo elective MVD surgery; 2. Aged 18-70 years old; 3. Primary HFS confirmed by clinical and imaging examination; 4. Volunteer to participate in the study and can provide written informed consent.
Exclusion criteria
Exclusion criteria: 1.Systemic administration (oral, intravenous, or intramuscular injection) of corticosteroids or non-steroidal anti-inflammatory drugs (NSAIDs) within 1 month before surgery (or long-term administration). Note: Topical corticosteroids (e.g., creams, inhalants) and topical NSAIDs (e.g., eye drops) are permitted. 2.A history of long-term (> 1 month) glucocorticoid therapy. 3.A confirmed diagnosis of endocrine diseases (e.g., Cushing’s syndrome, adrenal insufficiency, uncontrolled diabetes mellitus, hyperthyroidism, or hypothyroidism). 4.Presence of systemic inflammatory diseases or autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus). 5.Severe cardiac, hepatic, or renal insufficiency (Child-Pugh classification Grade C, or estimated glomerular filtration rate < 30 mL/min/1.73m²). 6.Contraindications to corticosteroid use, including preoperative active infection, peptic ulcer disease, or a history of mental illness. All patients must agree not to use NSAIDs or corticosteroids routinely without authorization during the follow-up period unless prescribed by a physician, and any such medication use must be recorded in detail. 7.Pregnancy or lactation period. 8.Inability to cooperate with follow-up or scale assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache Visual Analogue Scale (VAS) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Cortisol;Interleukin-6, IL-6;C-reactive protein, CRP; | — |
Countries
China
Contacts
Public ContactYinfu Xu
The Second People's Hospital of Liaocheng City
Outcome results
None listed