Postoperative nausea and vomiting
Conditions
Interventions
Standard two-handed mask positive pressure ventilation group:After loss of consciousness, participants received an intravenous injection of rocuronium bromide at a dose of 0.6 mg/kg. Anesthesiologists
Apnea group:After loss of consciousness, rocuronium bromide (0.6 mg/kg) was administered intravenously to the patients, and 100% oxygen was delivered via a face mask at a flow rate of 6 L/min without
apnea was maintained for 1 minute simultaneously.
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.American Society of Anesthesiologists (ASA) physical status ?-? 2.Aged 18 to 80 years old 3.Body mass index (BMI) ranging from 18.5 to 28 kg/m² 4.Fewer than 2 of the 5 criteria for predicting difficult mask ventilation (DMV) were met 5.Scheduled to undergo elective laparoscopic cholecystectomy (LC) 6.No other severe comorbidities
Exclusion criteria
Exclusion criteria: 1.A known or predicted respiratory system disease. 2.At risk of hypoxia or gastroesophageal reflux (including anticipated or a history of difficult intubation, pre-induction oxygen saturation < 90%, fasting time < 8 h, pregnancy, a history of gastroesophageal surgery, and loss of consciousness). 3.Pregnant or lactating women. 4.Patients with severe heart, liver, kidney or other severe organic diseases. 5.Patients who refused to participate or were unable to cooperate with the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score for postoperative nausea and vomiting;Number of postoperative retching and vomiting episodes;Frequency and dosage of postoperative antiemetic drug administration;Ultrasound assessment of the cross-sectional area of the gastric antrum in the supine position;Visual assessment of gastric distension severity under laparoscopy;Vital signs during anesthesia induction; | — |
Countries
China
Contacts
Public ContactQi Shiyuan
Shanghai East Hospital
Outcome results
None listed