Nasopharyngeal carcinoma
Conditions
Interventions
Gold Standard:Pathological examination
Index test:Two-step antibody and nucleic acid screening (serum EBNA-IgA and P85 antibody screening, plasma EBV DNA quantitative screening combined with sequencing if any positive)
Sponsors
Fifth Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
30 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1.Enrollment in the “Xijiang Project” screening cohort. 2.Age between 30 and 69 years at the time of screening.
Exclusion criteria
Exclusion criteria: 1.Known severe medical comorbidities, dysfunction of major organs (heart, lung, liver, or kidney), or neuropsychiatric disorders. 2.A history of malignant tumors. 3.Severe autoimmune diseases or an immunosuppressed state. 4.Women of childbearing age who test positive on a pregnancy test at the time of initial screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive Predictive Value(PPV);Negative Predictive Value( NPV); | — |
Countries
China
Contacts
Public ContactChen Mingyuan
Fifth Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed