Gestational diabetes mellitus
Conditions
Interventions
Intervention Group for Pregnant Women at High Risk of GDM:Individualized Medical Nutrition Assessment and Guidance: While ensuring adequate nutrition during pregnancy, control the total daily energy i
Control Group for Pregnant Women at High Risk of GDM:Routine pregnancy Care
Low-Risk GDM Pregnant Women Group:Routine pregnancy Care
Sponsors
Union Shenzhen Hospital of Huazhong University of Science and Technology
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Aged 20-45 years, with singleton pregnancy; 2.No prior diagnosis of diabetes and no family history of diabetes; 3.Scheduled for prenatal checkups and delivery at the Department of Obstetrics, Nanshan People's Hospital, Shenzhen, with complete clinical information and test results.
Exclusion criteria
Exclusion criteria: 1.Age less than 20 years or greater than 45 years; 2.Pre-pregnancy diagnosis of Type 1 or Type 2 diabetes, or a family history of diabetes; 3.Presence of other chronic diseases such as chronic hepatitis, hyperthyroidism, kidney disease, etc.; 4.Use of antibiotics or corticosteroids within the past three months; 5.Physical disability that impairs normal mobility, or intellectual or mental disorders that prevent cooperation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood glucose;fasting insulin level;Insulin Resistance Index;Incidence of gestational diabetes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin ß-cell function index;Quantitative Insulin Sensitivity Check Index;Non-targeted metabolomics;Protein quantitative proteomics;Remission rate of gestational diabetes;The incidence of impaired fasting blood glucose and diabetes at 42 Days Postpartum;The rate of change in insulin levels;Adverse pregnancy Incidence of pregnancy outcomes;Incidence of adverse events;Newborn birth weight;Newborn birth length;Newborn head circumference;Apgar score (newborns at 1 minute and 5 minutes after birth);Height;Weight; | — |
Countries
China
Contacts
Public ContactDeng Guifang
Union Shenzhen Hospital of Huazhong University of Science and Technology
Outcome results
None listed