Obstructive sleep apnea, OSA
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Complete standard polysomnography or home sleep apnea monitoring. (2) The subject himself or his legally - significant guardian agrees to participate in this clinical trial, signs the informed consent form, and is able to understand and comply with the requirements of the trial protocol.
Exclusion criteria
Exclusion criteria: (1) Subjects who refuse to sign the informed consent form or other situations where the researcher deems the subject ineligible to participate; (2) Patients with central sleep apnea syndrome; (3) Subjects who are unable to cooperate in providing specimens such as feces, saliva, and blood; (4) Subjects who have mental illnesses and are unable to cooperate; (5) Subjects suffering from diseases known to affect the gut microbiota, such as inflammatory bowel disease and intestinal tumors; (6) Subjects with diseases affecting the oral microbiota, such as severe periodontitis; (7) Any other diseases and conditions that the researcher believes may affect the experimental protocol or make the subject unsuitable for participation in this clinical project.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AHI;16S sequencing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolomics sequencing; | — |
Countries
China
Contacts
Zhongda Hospital Southeast University