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Study on the association between multi-site microbiome and host metabolome in obstructive sleep apnea

Study on the association between multi-site microbiome and host metabolome in obstructive sleep apnea

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600117453
Enrollment
Unknown
Registered
2026-01-23
Start date
2026-01-26
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea, OSA

Interventions

control group:no
Mild group :no
moderate group:no
severe group:no

Sponsors

Zhongda Hospital Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Complete standard polysomnography or home sleep apnea monitoring. (2) The subject himself or his legally - significant guardian agrees to participate in this clinical trial, signs the informed consent form, and is able to understand and comply with the requirements of the trial protocol.

Exclusion criteria

Exclusion criteria: (1) Subjects who refuse to sign the informed consent form or other situations where the researcher deems the subject ineligible to participate; (2) Patients with central sleep apnea syndrome; (3) Subjects who are unable to cooperate in providing specimens such as feces, saliva, and blood; (4) Subjects who have mental illnesses and are unable to cooperate; (5) Subjects suffering from diseases known to affect the gut microbiota, such as inflammatory bowel disease and intestinal tumors; (6) Subjects with diseases affecting the oral microbiota, such as severe periodontitis; (7) Any other diseases and conditions that the researcher believes may affect the experimental protocol or make the subject unsuitable for participation in this clinical project.

Design outcomes

Primary

MeasureTime frame
AHI;16S sequencing;

Secondary

MeasureTime frame
Metabolomics sequencing;

Countries

China

Contacts

Public ContactDing wenxiao

Zhongda Hospital Southeast University

wenxiaoding@163.com+86 136 0519 2643

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026