Total Hip Arthroplasty
Conditions
Interventions
Group O:oxycodone
Sponsors
The Second Hospital of Jiaxing
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age 65–80 years, BMI 18–28 kg/m^2, ASA I–III;
Exclusion criteria
Exclusion criteria: 1.Undergoing bilateral total hip arthroplasty, hip revision surgery, or anterior approach total hip arthroplasty; 2.preoperative coagulation abnormalities; 3.infection at the puncture site; 4.allergies to local anesthetics, general anesthetics, or related components; 5.significant organ dysfunction; 6.peripheral neuropathy; 7.hearing impairment and aphasia; 8.history of long-term use of analgesics or psychiatric medications; 9.preoperative cognitive impairment; 10.allergies to all medications used and their components.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time to first postoperative flatus; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-40 scores on the day before surgery, the first day after surgery and the third day after surgery;VAS scores at rest and during activity at 4, 12, 24, 48, and 72 hours postoperatively;MoCA scores at 24 hours before surgery, 24 hours after surgery and 48 hours after surgery;Awakening time, extubation time, Ramsay sedation score after extubation, PACU stay duration, time to first postoperative anal flatus, time to first postoperative ambulation, postoperative hospital sta;Occurrence of adverse reactions within 24 hours post-operation, including nausea, vomiting, skin itching, dizziness, drowsiness, respiratory depression, and arrhythmia.; | — |
Countries
China
Contacts
Public ContactHongmei Zhou
The Second Hospital of Jiaxing
Outcome results
None listed